We have been using the microscopic nematode, C. elegans, in the classroom to discuss transcription, translation, mutation, behavior and neurobiology. Students in Darci Kimball's Castle Park High School have really been enjoying their work with this fun organism!
As part of the transcription and translation unit, I had the students perform and RNA interference, or RNAi, procedure. Using RNAi, the students were able to deplete the collagen protein, DPY-10, which is similar to the protein that is found in our skin.
In addition to the RNAi activity, I have also developed another activity, which can be used in the neurobiology unit, that looks at the effects of ethanol on worm behavior.